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15‏/05‏/2010

هل المكسرات تخفض معدلات الكولسترول؟ Nuts & Cholesterol




كشفت دراسة أمريكية فى جامعة لوما ليندا فى كاليفورنيا نشرتها دورية أرشيف الطب الداخلى، عن أن تناول المكسرات يساهم فى خفض معدلات الكوليستيرول.

ونوهت جوان ساباتى معدة الدراسة بعدم تناول أكثر من 85 جراماً من المكسرات يومياً، وأجريت الدراسة على 583 شخصاً، حيث إن معدل الكولسترول لديهم عادى أو مرتفع، ولم يتناولوا أدوية لتخفيض معدلات الدهون، وقد تناول المشاركون فى الدراسة حوالى 67 جراماً من المكسرات فى اليوم "لوز وجوز وغيرها".


وأظهرت الدراسة أن تناول المكسرات ارتبط بتراجع بنسبة 5.1 % فى معدل تركيز الكولسترول، وتراجع بنسبة 7.4% فى معدل البروتين الدهنى منخفض الكثافة.

المصدر

اليوم السابع


Nut Consumption and Blood Lipid Levels

A Pooled Analysis of 25 Intervention Trials

Joan Sabaté, MD, DrPH; Keiji Oda, MA, MPH; Emilio Ros, MD, PhD

Arch Intern Med. 2010;170(9):821-827.

Background Epidemiological studies have consistently associated nut consumption with reduced risk for coronary heart disease. Subsequently, many dietary intervention trials investigated the effects of nut consumption on blood lipid levels. The objectives of this study were to estimate the effects of nut consumption on blood lipid levels and to examine whether different factors modify the effects.

Methods We pooled individual primary data from 25 nut consumption trials conducted in 7 countries among 583 men and women with normolipidemia and hypercholesterolemia who were not taking lipid-lowering medications. In a pooled analysis, we used mixed linear models to assess the effects of nut consumption and the potential interactions.

Results With a mean daily consumption of 67 g of nuts, the following estimated mean reductions were achieved: total cholesterol concentration (10.9 mg/dL [5.1% change]), low-density lipoprotein cholesterol concentration (LDL-C) (10.2 mg/dL [7.4% change]), ratio of LDL-C to high-density lipoprotein cholesterol concentration (HDL-C) (0.22 [8.3% change]), and ratio of total cholesterol concentration to HDL-C (0.24 [5.6% change]) (P < .001 for all) (to convert all cholesterol concentrations to millimoles per liter, multiply by 0.0259). Triglyceride levels were reduced by 20.6 mg/dL (10.2%) in subjects with blood triglyceride levels of at least 150 mg/dL (P < .05) but not in those with lower levels (to convert triglyceride level to millimoles per liter, multiply by 0.0113). The effects of nut consumption were dose related, and different types of nuts had similar effects on blood lipid levels. The effects of nut consumption were significantly modified by LDL-C, body mass index, and diet type: the lipid-lowering effects of nut consumption were greatest among subjects with high baseline LDL-C and with low body mass index and among those consuming Western diets.

Conclusion Nut consumption improves blood lipid levels in a dose-related manner, particularly among subjects with higher LDL-C or with lower BMI.

Source

Archives of Internal Medicine

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